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1.
J Am Anim Hosp Assoc ; 60(3): 114-119, 2024 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-38662995

RESUMEN

Snake envenomation is relatively common in small animals, particularly in endemic areas. Effects and outcomes of envenomation during pregnancy are poorly described in humans and more so in veterinary patients. Two young pregnant female dogs presented to a university teaching hospital with a history of acute soft tissue swelling and bleeding. History, physical examination findings, and diagnostics were consistent with envenomation by crotalid snakes. Medical management of one of the dogs included administration of antivenin. Both dogs survived envenomation with minimal complications and went on to whelp without complications, and all fetuses survived. This is the first description of the management of pit viper envenomation in pregnant dogs.


Asunto(s)
Antivenenos , Enfermedades de los Perros , Mordeduras de Serpientes , Animales , Perros , Mordeduras de Serpientes/veterinaria , Mordeduras de Serpientes/terapia , Mordeduras de Serpientes/complicaciones , Femenino , Embarazo , Enfermedades de los Perros/etiología , Enfermedades de los Perros/patología , Antivenenos/uso terapéutico , Complicaciones del Embarazo/veterinaria , Venenos de Crotálidos/envenenamiento , Venenos de Crotálidos/toxicidad , Viperidae
2.
Cureus ; 16(1): e51868, 2024 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-38327943

RESUMEN

OBJECTIVE: Digitally reconstructed radiographs (DRRs) are planar two-dimensional (2D) X-rays derived from a three-dimensional (3D) computed tomography (CT) dataset. DRRs allow the simulation of radiographs of all desired views and facilitate preoperative planning. However, orthopedic surgeons rely on C-arm fluoroscopic imaging during surgery to verify fracture reduction and implant placement. Pincushion distortion represents a technical limitation of fluoroscopic imaging, resulting in a greater distance between points at the periphery of the image compared to the center. This project, therefore, aimed to assess the image correlation between digitally reconstructed radiographs (DRRs) and fluoroscopic imaging (C-arm) using conventional radiographs (X-ray) as a control. METHODS: A 3D-printed cubic prototype and an anatomical humerus bone model were used. C-arm fluoroscopic radiographs and conventional X-ray images were taken in an anteroposterior (AP) view at 10-degree steps while rotating the objects from 0 to 90 degrees. CT scans were made and used to compute and export DRRs in AP view at 10-degree rotational steps from 0 to 90 degrees. The surface area (cm2) was measured and compared between the different modalities. For automated image analysis of the anatomical humerus model, matching (%) between modalities was calculated using the structural similarity index (SSIM). RESULTS: The overall regression was statistically significant in all models, with an R2 >0.99 when comparing all three imaging modalities of the prototype. Surface correlation in the anatomical humerus model was R2 0.99 between X-ray and C-arm and R2 0.95 between C-arm and X-ray to DRRs, respectively. The SSIM was highest for comparing DRR and C-arm images (0.84±0.01%). CONCLUSIONS: The study indicates a strong agreement between digitally reconstructed radiographs and X-ray/C-arm images. DRRs, therefore, represent a valuable tool for research and clinical application.

3.
Toxicon ; 229: 107134, 2023 Jun 15.
Artículo en Inglés | MEDLINE | ID: mdl-37160192

RESUMEN

The medical records of 95 pit viper envenomations in client-owned dogs presented to an academic emergency hospital in the Southeastern United States during the period spanning 2018 and 2020 were retrospectively examined. This study's primary objectives were to record the clinical abnormalities and treatment responses associated with envenomation and their relation to outcome. Approximately 80% of the bites involved the head region associated with varying degrees of hemorrhagic lymphedema. Some of the most common additional symptoms observed were; hypotension (10%), cardiac dysrhythmias (17%), and coagulopathy (21%). Treatment in most cases consisted of intravenous fluids, antivenom, and analgesic drugs. Blood products were used as indicated for anemia and persistent bleeding. The average dose of the F('ab')2 was 1-2 vials. Additional vials (3-22) were administered as needed to counteract persistent or recurrent coagulopathy and hemolysis. Only 3% of the dogs had mild clinical signs of Type 1 hypersensitivity during their treatment period. Antihistamine use at the tertiary hospital was restricted to the three dogs showing signs of a suspected allergic reaction in response to antivenom administration; these patients received diphenhydramine intramuscularly. A glucocorticoid drug was used in only one dog prior to referral but not subsequently. Ninety dogs had a good outcome, while five died. Historically, pit viper envenomation in dogs in the southeastern United States has been a potentially life-threatening problem. Most dogs will survive if treated promptly and appropriately with adequate amounts of intravenous fluids, and antivenom titrated on severity of clinical presentation.


Asunto(s)
Trastornos de la Coagulación Sanguínea , Crotalinae , Mordeduras de Serpientes , Viperidae , Animales , Perros , Antivenenos/uso terapéutico , Mordeduras de Serpientes/tratamiento farmacológico , Mordeduras de Serpientes/epidemiología , Mordeduras de Serpientes/complicaciones , Florida/epidemiología , Estudios Retrospectivos , Trastornos de la Coagulación Sanguínea/tratamiento farmacológico
4.
Toxicon X ; 18: 100156, 2023 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-37168094

RESUMEN

A 2-year-old female Dachshund had a witnessed timber rattlesnake envenomation. Although rattlesnake envenomations are a common, potentially life-threatening event in companion animals, timber rattlesnake envenomations in the dog are rarely reported. This dog described in this case report had significant hematologic and neurologic clinical derangements consistent with Types A and B rattlesnake venom and a suspected hypersensitivity reaction to the venom. This patient was treated aggressively with antivenom and fully recovered without any persistent neurologic signs at follow-up.

5.
Clin Case Rep ; 9(11): e05065, 2021 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-34804530

RESUMEN

Treatment of pit viper envenomated puppies (≤6  months old) with antivenom was well tolerated, similar to adult dogs. However, therapeutic guidelines should be established to direct use and prove efficacy in this population.

6.
Arch Orthop Trauma Surg ; 141(9): 1559-1565, 2021 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-33555404

RESUMEN

PURPOSE: The purpose of this study was to evaluate the intermediate-term clinical and radiological outcomes for acute, unstable acromioclavicular joint (ACJ) injuries treated with the arthroscopically assisted BiPOD stabilisation technique. METHODS: Twenty-three patients who sustained acute, unstable ACJ injuries were included in this prospective study. We recorded demographics, injury classification, time to surgery, clinical scores, radiological outcomes and complications; each patient completed a minimum of 2 years post-operative observation. RESULTS: Mean follow-up was 26 months (range, 24-34). Clinical outcomes scores demonstrated good 2-year results: relative Constant score, 97.9/100; ACJ Index, 89.4/100; Subjective Shoulder Value, 92.4/100 and Taft = 11.1/12. Final C-C distance showed a mean of 0.7 mm (SD ± 1.8 mm) at 2 years. Complication rate was 9%. CONCLUSION: The BiPOD technique shows excellent, reliable intermediate-term results with a favourable complication rate compared to existing techniques; it provides a comprehensive surgical option for the stabilisation of acute ACJ injuries restoring both vertical and horizontal stability.


Asunto(s)
Articulación Acromioclavicular , Articulación Acromioclavicular/diagnóstico por imagen , Articulación Acromioclavicular/cirugía , Humanos , Luxaciones Articulares , Ligamentos Articulares , Estudios Prospectivos , Resultado del Tratamiento
7.
J Knee Surg ; 34(5): 561-569, 2021 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-31683352

RESUMEN

The purpose of this study is to determine the effect of the magnitude of static mechanical tension on the anterior cruciate ligament (ACL) graft at the time of surgery on healing within the graft tunnels. Ninety male rats underwent unilateral ACL resection followed by reconstruction with a soft tissue tendon autograft. The ACL graft mechanical environment was modulated by different ACL graft pretension levels at the time of surgery (no pretension: 0N; moderate tension: 5N; over tension: 10N). External fixators were used to eliminate graft and joint motion during cage activity. Graft-tunnel healing was assessed at 3- and 6-week postoperatively, and articular joint surfaces were assessed at 9 weeks. Our results demonstrate that the ACL graft-tunnel healing was sensitive to different static graft pretension levels as demonstrated by different load-to-failure and stiffness properties among the different pretension levels. Pretensioning the graft to 5N (7-8% of the rat ACL ultimate load to failure) resulted in the best graft-tunnel healing as shown by higher graft-tunnel failure load and stiffness. Higher bone volume fraction was also seen in the 5N group relative to other pretension levels. Histological analysis of the graft-tunnel interface revealed differences in cellularity of the ACL graft between the 5N group and the other two groups. Furthermore, the highest graft pretension level (10N) resulted in loss of proteoglycan content among articular joint surfaces. In conclusion, we found that ACL graft-tunnel healing is sensitive to the magnitude of graft pretension at the time of surgery in a preclinical model of ACL reconstruction with joint immobilization. The combination of high-graft tension and immobilization is also deleterious for the articular surface. Further study is necessary to understand the interaction between the magnitude of graft tensioning and joint motion.


Asunto(s)
Lesiones del Ligamento Cruzado Anterior/cirugía , Reconstrucción del Ligamento Cruzado Anterior/métodos , Ligamento Cruzado Anterior/cirugía , Animales , Ligamento Cruzado Anterior/diagnóstico por imagen , Ligamento Cruzado Anterior/patología , Lesiones del Ligamento Cruzado Anterior/diagnóstico por imagen , Lesiones del Ligamento Cruzado Anterior/patología , Fémur/diagnóstico por imagen , Fémur/cirugía , Masculino , Distribución Aleatoria , Ratas , Estrés Fisiológico , Tendones/diagnóstico por imagen , Tendones/patología , Tendones/trasplante , Trasplante Autólogo , Cicatrización de Heridas , Microtomografía por Rayos X
8.
Toxicon ; 191: 38-43, 2021 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-33316296

RESUMEN

Thirty cats were identified to be have been suspected to have a potential coral snake envenomation after searching medical records from 2012 to 2019 at a university teaching hospital. The records were reviewed and evaluated for signalment, date and time of the snake encounter, elapsed time between encounter and hospital examination, presenting complaint, initial physical examination findings, initial laboratory findings, antivenom dose and duration of administration, adverse reactions to antivenom, additional treatments administered, progression of clinical signs, length of hospitalization, and outcome. Thirteen cats presented with clinical signs consistent with envenomation while 17 cats were treated for possible asymptomatic envenomation, as defined by the owner discovering a live or dead coral snake in their home or on their property. Initial physical examination findings included tachypnea with short shallow breaths and use of accessory muscles; tetraparesis with normal or decreased to absent spinal reflexes; cranial nerve deficits including decreased to absent gag, slow pupillary light reflexes, and absent physiologic nystagmus; and normal or altered mentation. Laboratory findings included hypercapnia, hyperglycemia, hypokalemia, increased aspartate aminotransferase activity, increased alanine aminotransferase activity, echinocytosis, leukocytosis, azotemia, and hyperlactatemia. Twenty-eight cats received antivenom; two cats received two vials while twenty-six cats received one vial. Antivenom reaction was suspected in one cat that developed facial swelling during administration of the drug. Average length of hospitalization was 1 day for cats without clinical signs and 3 days for cats with clinical signs. Twenty-nine cats survived to discharge. Due to the inclusion criteria of the study, cats euthanized on presentation or discharged without receiving antivenom may have been unintentionally excluded from the study. Diagnosis of eastern coral snake envenomation should be suspected in the cat that has acute onset of lower motor neuron neuropathy. Prognosis with treatment is considered good with 97% of cats surviving to discharge. Antivenom reaction occurred in 3.5% of administrations with none being fatal. Monitoring of hypercapnia was critical in making the decision to mechanically ventilate patients. Supportive care that includes antivenom administration, recumbency care, and mechanical ventilation if needed are the mainstays of therapy.


Asunto(s)
Antivenenos/uso terapéutico , Serpientes de Coral , Mordeduras de Serpientes/epidemiología , Animales , Gatos , Hospitalización , Hospitales Universitarios , Humanos , Mordeduras de Serpientes/tratamiento farmacológico
9.
Clin Case Rep ; 8(12): 3498-3502, 2020 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-33363959

RESUMEN

Although neoplasia should be a top concern for extreme leukocytosis in dogs, infectious causes must also be considered to avoid delays in treatment or undue recommendations for humane euthanasia. Blood film review is of paramount importance.

10.
Ther Umsch ; 77(5): 189-198, 2020 Jun.
Artículo en Alemán | MEDLINE | ID: mdl-32870102

RESUMEN

Traumatic dislocation of the shoulder - a guide for medical practicioners Abstract. Traumatic dislocation of the shoulder joint is a common injury. Young patients suffer from dislocations usually during leisure and competitive activities, the elderly are prone for injuries because of falls. We provide an overview about state-of-the-art management in first traumatic shoulder dislocations. Besides an overview for mechanisms leading to injuries, we describe first line therapy as well as techniques to reposition the shoulder. First time traumatic glenohumeral dislocations can usually be treated without surgery, we elucidate the topic regarding the need for further imaging as well as possible injuries accompanying the dislocation.


Asunto(s)
Luxación del Hombro/diagnóstico , Articulación del Hombro , Anciano , Humanos , Hombro
11.
J Vet Emerg Crit Care (San Antonio) ; 30(6): 698-705, 2020 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-32975046

RESUMEN

OBJECTIVES: To describe the clinicopathological characteristics of dogs that develop acute kidney injury (AKI) secondary to pit viper envenomation, and to describe the association between development of AKI and clinical course and outcome. DESIGN: Retrospective study. SETTING: University teaching hospital. ANIMALS: Client-owned dogs treated with at least 1 vial of antivenom following pit viper envenomation and that had at least 2 plasma creatinine concentrations measured during the course of hospitalization. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Sixty-three dogs met the inclusion criteria. One was excluded due chronic kidney disease, and 6 were excluded due to nonsteroidal anti-inflammatory drug administration. Of the 56 dogs included in the study, 16 developed AKI (29%). Dogs with AKI received a significantly higher dose of antivenom, 8.7 ± 6.8 total vials versus dogs in the non-AKI group that received 4.2 ± 2.6 vials (P = 0.006). Dogs in the AKI group were significantly more tachycardic (P = 0.028), hypotensive (P = 0.002), had a higher shock index (P = 0.012), and were more likely to receive transfusions with packed red blood cells (P = 0.042) than dogs in the non-AKI group. No significant association was identified between the development of AKI and length of hospitalization. The only factors that were significantly associated with degree of severity of AKI included the receipt of blood transfusion (P = 0.006) and number of vials of antivenom administered (P = 0.03). The development of AKI was significantly associated with outcome (P < 0.001), with 5 of 16 (31%) dogs in the AKI group surviving to discharge, 7 of 16 (44%) dying, and 4 of 16 (25%) being euthanized versus 39 of 40 (98%) surviving to discharge in the non-AKI group and 1 of 40 (2%) dying in hospital. CONCLUSION: Development of AKI in dogs following pit viper envenomation carries an increased risk of mortality that is associated with severity of shock at presentation and increased doses of antivenom administration.


Asunto(s)
Lesión Renal Aguda/veterinaria , Antivenenos/uso terapéutico , Crotalinae , Enfermedades de los Perros/etiología , Mordeduras de Serpientes/veterinaria , Lesión Renal Aguda/complicaciones , Animales , Venenos de Crotálidos/uso terapéutico , Enfermedades de los Perros/patología , Enfermedades de los Perros/terapia , Perros , Femenino , Hipotensión/veterinaria , Masculino , Estudios Retrospectivos , Mordeduras de Serpientes/complicaciones , Mordeduras de Serpientes/terapia
12.
Can Vet J ; 61(4): 411-414, 2020 04.
Artículo en Inglés | MEDLINE | ID: mdl-32255828

RESUMEN

This report details an unusual clinical presentation of suspected acute pancreatitis that occurred after honeybee envenomation in a dog. A 13-year-old spayed female dog was presented for further evaluation of vomiting 3 days after honeybee envenomation. Abdominal ultrasound, fine-needle aspirate cytology, and blood analysis were used to establish the diagnosis. The dog recovered following supportive care. While bee envenomation induced acute pancreatitis has been reported in human literature, to the authors' knowledge, this is the first reported case in a dog in which pancreatitis ensued soon after envenomation. Key clinical message: This report describes a case of a dog with honeybee envenomation that subsequently developed acute pancreatitis. Given the widespread presence of the honeybee across the globe, while rare, it is important that clinicians are aware of potential envenomation sequelae such as acute pancreatitis.


Suspicion de pancréatite aigüe chez un chien à la suite d'une envenimation par des abeilles. Le présent rapport donne les détails d'une présentation clinique inhabituelle d'une suspicion de pancréatite aigüe qui est survenue à la suite d'une envenimation par des abeilles chez un chien. Une chienne stérilisée âgée de 13 ans fut présentée pour évaluation plus poussée de vomissements 3 jours après envenimation par des abeilles. Une échographie abdominale, une cytologie d'aspiration à l'aiguille fine et une analyse sanguine furent utilisées afin d'établir le diagnostic. La chienne a récupéré à la suite d'un traitement de support. Alors que l'envenimation par les abeilles induisant une pancréatite aigüe a été rapportée dans la littérature humaine, à la connaissance de l'auteur ceci est le premier cas rapporté chez le chien dans lequel une pancréatite est apparue peu de temps après l'envenimation.Message clinique clé:Ce rapport décrit le cas d'un chien avec envenimation par des abeilles qui développa subséquemment une pancréatite aigüe. Étant donné la présence répandue des abeilles à travers le globe, bien que rare, il est important que les cliniciens soient au fait des séquelles potentielles d'une envenimation telle qu'une pancréatite aigüe.(Traduit par Dr Serge Messier).


Asunto(s)
Enfermedades de los Perros , Pancreatitis/veterinaria , Enfermedad Aguda , Animales , Abejas , Perros , Ojo , Femenino , Humanos , Vómitos/veterinaria
13.
J Vet Emerg Crit Care (San Antonio) ; 30(3): 331-335, 2020 May.
Artículo en Inglés | MEDLINE | ID: mdl-31944542

RESUMEN

OBJECTIVE: To describe the clinical presentation and outcome of a dog with primary hypoparathyroidism secondary to cervical bite wounds. CASE SUMMARY: A 3-year-old male intact Chihuahua presented after being attacked by a large breed dog. The dog sustained severe cervical lacerations, exposing the trachea and jugular veins. A portion of the right thyroid gland was missing. The dog was stabilized before wound debridement and closure. Ionized calcium concentrations were within reference range at the time of presentation. Forty-eight hours after the initial trauma, the dog was presented in lateral recumbency with signs of hypovolemic shock, muscle tremors, and hyperthermia. Bloodwork showed severe ionized hypocalcemia with low normal parathyroid hormone concentration consistent with acute primary hypoparathyroidism. The dog was managed initially with IV calcium gluconate and calcitriol, then long-term oral calcium carbonate and vitamin D3. After 6 months, the dog was successfully weaned off calcium supplementation. NEW OR UNIQUE INFORMATION PROVIDED: This is the first described case of traumatic primary hypoparathyroidism after a bite injury to the neck in a dog.


Asunto(s)
Mordeduras y Picaduras/veterinaria , Enfermedades de los Perros/etiología , Hipoparatiroidismo/veterinaria , Animales , Mordeduras y Picaduras/complicaciones , Calcio/sangre , Gluconato de Calcio/farmacología , Colecalciferol/administración & dosificación , Colecalciferol/uso terapéutico , Enfermedades de los Perros/patología , Perros , Femenino , Humanos , Hipocalcemia/etiología , Hipocalcemia/veterinaria , Hipoparatiroidismo/tratamiento farmacológico , Hipoparatiroidismo/etiología , Hipoparatiroidismo/patología , Masculino , Hormona Paratiroidea , Heridas y Lesiones
14.
BMC Musculoskelet Disord ; 20(1): 604, 2019 Dec 12.
Artículo en Inglés | MEDLINE | ID: mdl-31831070

RESUMEN

BACKGROUND: Early femoral stem subsidence following a cementless THA is correlated with aseptic loosening of the femoral component. The short femoral stems allow bone sparing and implantation through a minimally invasive approach; however, due to their metaphyseal anchoring, they might demonstrate different subsidence pattern than the conventional stems. METHODS: In this prospective single-center study, a total of 68 consecutive patients with an average age of 63 years, and a minimum follow-up of 5 years following a cementless THA with a metaphyseal-anchored short femoral stem were included. The femoral stem subsidence was evaluated using "Ein Bild Roentgen Analyse" (EBRA). RESULTS: Average stem migration was 0.96 +/- 0.76 mm at 3 months, 1.71 +/- 1.26 mm at 24 months, and 2.04+/- 1.42 mm at last follow-up 60 months postoperative. The only factor that affected migration was a stem size of 6 or more (r2 = 5.74; p = 0.039). Subdivision analysis revealed, that only in females migration appeared to be affected by stem size irrespective of weight but not in men (female stem size of 6 or more vs. less (Difference = - 1.48 mm, R2 = 37.5; p = 0.001). Migration did not have an impact on clinical outcome measures. CONCLUSIONS: The examined metaphyseal-anchored short femoral stem showed the highest subsidence within the first 3 months postoperative, the implant began to stabilize at about 24 months but continued to slowly migrate with average total subsidence of 2.04 mm at 5 years following the THA. The amount of stem subsidence was not associated with worse clinical outcomes such as HHS, patient satisfaction, or pain.


Asunto(s)
Artroplastia de Reemplazo de Cadera/efectos adversos , Migración de Cuerpo Extraño/etiología , Prótesis de Cadera/efectos adversos , Falla de Prótesis/etiología , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Prospectivos
15.
J Vet Emerg Crit Care (San Antonio) ; 29(6): 662-667, 2019 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-31625672

RESUMEN

OBJECTIVE: To describe the use of mechanical ventilation (MV) in the management of Eastern coral snake envenomation in 7 dogs and a cat. DESIGN: Retrospective study (2011-2016). SETTING: University teaching hospital. ANIMALS: Seven dogs and 1 cat receiving MV for ventilatory failure secondary to Eastern coral snake envenomation. INTERVENTIONS: None. MEASUREMENT AND MAIN RESULTS: The medical records of 8 animals that received MV following Eastern coral snake envenomation were reviewed. Data collected included signalment, time to veterinary assessment, physical and laboratory characteristics at arrival, clinical course during hospitalization, management including antivenom administration, MV settings, duration of ventilation, length of hospitalization, cost of care, and survival to discharge. The mean ± SD age was 4 ± 3.2 years. Median (range) time to onset of clinical signs was 30 (5-240) minutes. Coral snake antivenom was administered to 7 of the 8 animals following arrival at a median (range) of 30 (5-90) minutes. All animals had progressive hypoventilation and received MV, specifically volume controlled, synchronized intermittent mandatory ventilation with pressure support. The median (range) duration of MV was 58 (25-84) hours and the median (range) duration of hospitalization was 8.2 (6-11) days. Ventilator associated complications occurred in all animals, but overall outcome was excellent with 7 of 8 surviving to discharge. No dog, but the 1 cat, had an adverse reaction to antivenom. CONCLUSIONS: Ventilatory failure secondary to Eastern coral snake envenomation necessitating MV carries an excellent prognosis and is better than reported for other causes of lower motor neuron disease. Successful response to ventilation was achieved even with associated complications being common in this cohort of animals.


Asunto(s)
Antivenenos/administración & dosificación , Serpientes de Coral , Respiración Artificial/veterinaria , Insuficiencia Respiratoria/veterinaria , Mordeduras de Serpientes/veterinaria , Proteínas Adaptadoras Transductoras de Señales , Animales , Gatos , Proteínas de Ciclo Celular , Estudios de Cohortes , Perros , Hospitalización , Hospitales Universitarios , Humanos , Masculino , Registros Médicos , Respiración con Presión Positiva , Insuficiencia Respiratoria/etiología , Insuficiencia Respiratoria/terapia , Estudios Retrospectivos , Mordeduras de Serpientes/terapia
16.
Toxicon ; 166: 83-87, 2019 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-31129161

RESUMEN

INTRODUCTION: North Central Florida is the home to several venomous snakes. The most clinically significant pit vipers include the Eastern Diamondback Rattlesnake, the Water Moccasin, and less commonly the Timber Rattlesnake. Many of the dogs and cats that become envenomated by these particular snakes have moderate to severe clinical signs requiring the use of antivenom in doses that can range from 1 to 20 vials with the average case requiring two vials. Oftentimes, the pet owners' financial limitations restrict the amount of antivenom that can be administered initially to severely envenomed cases. Most of these patients will become clinically stable after the first 48 hours of treatment, but there are rare instances where some patients will follow this same initial course, and then revert back to the initial signs of envenomation associated with delayed absorption of redistributed venom from other tissue sites in addition to the bite site. This report describes three dogs that showed signs of persistent and/or recurrent envenomation requiring additional doses of antivenom. METHODS: The medical records of three dogs showing signs of persistent envenomation were reviewed by the author who was available and provided assistance during the course of the dogs' respective hospitalizations. The dog's signalment, time of year of the envenomation, clinical signs, treatment, and outcome are provided in each case. RESULTS: Each of these three dogs showed severe signs of envenomation characterized by marked mental depression, prostration, hemorrhagic lymphedema, and evidence of prolonged coagulation times. Initial treatment in each consisted of intravenous crystalloid solution and polyvalent crotalid antivenom that exceeded the usual average dose as reported in the literature. After the coagulation test normalized during the first three days, all of them reverted to abnormal prolonged clotting times with signs of clinical deterioration requiring additional doses of antivenom. Clinical stability was eventually reached and all dogs survived to be discharged. CONCLUSIONS: The clinical course of the three dogs described in this study showed that veterinary patients can experience persistent envenomation in a similar manner as described in humans. It behooves the veterinary practitioner to be aware of this complication and to be prepared to extend antivenom treatment as deemed necessary.


Asunto(s)
Antivenenos/uso terapéutico , Crotalus , Enfermedades de los Perros/tratamiento farmacológico , Mordeduras de Serpientes/veterinaria , Animales , Antivenenos/administración & dosificación , Trastornos de la Coagulación Sanguínea/inducido químicamente , Trastornos de la Coagulación Sanguínea/tratamiento farmacológico , Trastornos de la Coagulación Sanguínea/veterinaria , Venenos de Crotálidos/antagonistas & inhibidores , Soluciones Cristaloides/administración & dosificación , Perros , Femenino , Masculino , Mordeduras de Serpientes/tratamiento farmacológico
17.
Knee Surg Sports Traumatol Arthrosc ; 26(1): 125-135, 2018 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-28547587

RESUMEN

PURPOSE: The aim of this study was to identify the most accurate and reliable quantitative radiographic parameters for assessing vertical and horizontal instability in different Rockwood grades of acromioclavicular joint (ACJ) separations. Furthermore, the effect of projectional variation on these parameters was investigated in obtaining lateral Alexander view radiographs. METHODS: A Sawbone model of a scapula with clavicle was mounted on a holding device, and acromioclavicular dislocations as per the Rockwood classification system were simulated with the addition of horizontal posterior displacement. Projectional variations for each injury type were performed by tilting/rotating the Sawbone construct in the coronal, sagittal or axial plane. Radiographic imaging in the form of an anterior-posterior Zanca view and a lateral Alexander view were taken for each injury type and each projectional variation. Five newly defined radiographic parameters for assessing horizontal and vertical displacement as well as commonly used coracoclavicular distance view were measured. Reliability, validity and the effect of projectional variation were investigated for these radiographic measurements. RESULTS: All radiographic parameters showed excellent intra- and interobserver reliability. The validity was excellent for the acromial centre line to dorsal clavicle (AC-DC) in vertical displacement and for the glenoid centre line to posterior clavicle (GC-PC) in horizontal displacement, whilst the remaining measurements showed moderate validity. For AC-DC and GC-PC, convergent validity expressed strong correlation to the effective distance and discriminant validity demonstrated its ability to differentiate between various grades of ACJ dislocations. The effect of projectional variation increased with the degree of deviation and was maximal (3 mm) for AC-DC in 20° anteverted malpositioning and for GC-PC in 20° retroverted malpositioning. CONCLUSIONS: AC-DC and the GC-PC are two novel quantitative radiographic parameters of vertical and horizontal instability in ACJ dislocations that demonstrate excellent reliability and validity with reasonable inertness to malpositioning. The use of AC-DC for assessing vertical displacement and GC-PC for assessing horizontal displacement in a single Alexander view is recommended to guide the appropriate management of ACJ dislocations. A better appreciation of the degree of horizontal instability, especially in lower Rockwood grades (II, III) of ACJ dislocations, may improve management of these controversial injuries.


Asunto(s)
Articulación Acromioclavicular/diagnóstico por imagen , Articulación Acromioclavicular/lesiones , Luxaciones Articulares/diagnóstico por imagen , Inestabilidad de la Articulación/diagnóstico por imagen , Acromion/diagnóstico por imagen , Clavícula/diagnóstico por imagen , Humanos , Luxaciones Articulares/clasificación , Inestabilidad de la Articulación/clasificación , Modelos Anatómicos , Reproducibilidad de los Resultados , Tomografía Computarizada por Rayos X
18.
JFMS Open Rep ; 3(2): 2055116917737463, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-29123914

RESUMEN

CASE SUMMARY: A 4-year-old female spayed, indoor/outdoor domestic mediumhair cat presented with multiple bleeding puncture wounds and hemorrhagic shock. The cat was diagnosed with suspected pit viper envenomation based on the location and appearance of the bite wounds, as well as the presence of severe coagulopathy with prolonged activated coagulation time (762 s), which responded to antivenom administration. The clinical course of the cat was unique owing to the prolonged clinical signs of envenomation that appeared as intermittent coagulopathy and hemorrhage over a 2 week period. Five vials of antivenom were administered and three units of packed red blood cells were transfused over a 7 day period. The cat made a complete recovery with cessation of hemorrhage and normalization of clotting times. RELEVANCE AND NOVEL INFORMATION: This is the first report of persistent pit viper venom-induced coagulopathy in the feline veterinary literature.

19.
Can Vet J ; 58(3): 265-269, 2017 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-28246414

RESUMEN

This report describes a case of honeybee envenomation in a dog that developed anaphylaxis after being stung by approximately 10 bees. The dog subsequently developed acute kidney injury. The dog had a previous mild increase in blood urea nitrogen with normal creatinine, possibly indicating an insidious chronic renal degenerative process that went into acute decompensation at the time of bee envenomation.


Lésion rénale chez un chien après l'anaphylaxie associée à une piqûre d'abeille. Ce rapport décrit un cas d'envenimement d'un chien qui a été piqué par environ 10 abeilles et a développé l'anaphylaxie puis une lésion rénale aiguë. Le chien avait eu une légère hausse antérieure de l'azote uréique du sang avec une créatinine normale, ce qui indique éventuellement un processus dégénératif rénal chronique insidieux qui s'est développé en une décompensation aiguë au moment de l'envenimement par les abeilles.(Traduit par Isabelle Vallières).


Asunto(s)
Lesión Renal Aguda/etiología , Anafilaxia/veterinaria , Abejas , Enfermedades de los Perros/etiología , Mordeduras y Picaduras de Insectos/veterinaria , Anafilaxia/etiología , Animales , Perros , Femenino , Mordeduras y Picaduras de Insectos/complicaciones
20.
Orthopedics ; 40(1): e35-e43, 2017 Jan 01.
Artículo en Inglés | MEDLINE | ID: mdl-27648574

RESUMEN

Stabilizing the acromioclavicular joint in the vertical and horizontal planes is challenging, and most current techniques do not reliably achieve this goal. The BiPOD repair is an arthroscopically assisted procedure performed with image intensifier guidance that reconstructs the coracoclavicular ligaments as well as the acromioclavicular ligaments to achieve bidirectional stability. Repair is achieved with a combination of 2-mm FiberTape (Arthrex, Naples, Florida) and 20-mm Poly-Tape (Neoligaments, Leeds, England) to achieve rigid repair, prevent bone abrasion, and promote tissue ingrowth. This study is a prospective review of the first 6 patients treated for high-grade acute acromioclavicular injury with the BiPOD technique. The study included 6 men who were 21 to 36 years old (mean, 27 years). At 6-month follow-up, complications were recorded and radiographic analysis was used to determine the coracoclavicular distance for vertical reduction and the amount of acromioclavicular translation on the Alexander axillary view was used to determine horizontal reduction. One patient had a superficial infection over the tape knot. The difference in coracoclavicular distance between the operated side and the uninvolved side was 9±2 mm preoperatively and 0.3±2 mm at 6-month follow-up. On Alexander axillary view, all 6 patients showed stable reduction, which is defined as a clavicle that is in line with the acromion. The findings show that BiPOD acromioclavicular reconstruction restores bidirectional stability of the acromioclavicular joint at 6 months. [Orthopedics. 2017; 40(1):e35-e43.].


Asunto(s)
Articulación Acromioclavicular/cirugía , Artroscopía/métodos , Clavícula/cirugía , Apófisis Coracoides/cirugía , Luxaciones Articulares/cirugía , Ligamentos Articulares/cirugía , Articulación Acromioclavicular/lesiones , Acromion , Adulto , Humanos , Masculino , Estudios Prospectivos , Procedimientos de Cirugía Plástica , Adulto Joven
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